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Synthesis and evaluation of a tetra[6,7] quinoxalinoporphyrazine-based near infrared photosensitizer
文献类型:期刊
作者:Shao, Pin[1]  Zhang, Shaojuan[2]  Hu, Shudong[3]  Han, Le[4]  Jia, Ningyang[5]  Bai, Mingfeng[6]  
机构:[1]Univ Pittsburgh, Dept Radiol, 100 Technol Dr, Pittsburgh, PA 15219 USA.;
[2]Univ Pittsburgh, Dept Radiol, 100 Technol Dr, Pittsburgh, PA 15219 USA.;
[3]Jiangsu Univ, Affiliated Renmin Hosp, Dept Radiol, Zhenjiang 212002, Jiangsu, Peoples R China.;
[4]Vanderbilt Univ, Med Ctr, Inst Imaging Sci, Nashville, TN 37232 USA.;
[5]Shanghai Eastern Hepatobiliary Surg Hosp, Dept Radiol, Shanghai 200438, Peoples R China.;
[6]Univ Pittsburgh, Dept Radiol, 100 Technol Dr, Pittsburgh, PA 15219 USA.;Univ Pittsburgh, Dept Med, 3501 Fifth Ave, Pittsburgh, PA 15213 USA.,Univ Pittsburgh, Dept Bioengn, Pittsburgh, PA 15261 USA.,Univ Pittsburgh, Canc Inst, Pittsburgh, PA 15232 USA.;
通讯作者:Bai, MF (reprint author), Univ Pittsburgh, Dept Radiol, 100 Technol Dr, Pittsburgh, PA 15219 USA.; Jia, NY (reprint author), Shanghai Eastern Hepatobiliary Surg Hosp, Dept Radiol, Shanghai 200438, Peoples R China.; Bai, MF (reprint author), Univ Pittsburgh, Dept Med, 3501 Fifth Ave, Pittsburgh, PA 15213 USA.; Bai, MF (reprint author), Univ Pittsburgh, Dept Bioengn, Pittsburgh, PA 15261 USA.; Bai, MF (reprint author), Univ Pittsburgh, Canc Inst, Pittsburgh, PA 15232 USA.
年:2017
期刊名称:RSC ADVANCES影响因子和分区
卷:7
期:80
页码范围:50555-50561
增刊:正刊
学科:化学
收录情况:SCI(E)(WOS:000414405800016)  EI(20174504378768)  PubMed(29456839)  
语言:外文
ISSN:2046-2069
人气指数:193
浏览次数:193
基金:NIH [R21CA174541]; Department of Radiology, University of Pittsburgh, Science and Technology Commission of Shanghai Municipality [14430723200, 14430723201]; National Nature Science Foundation of China [81671739]
摘要:Here we report a near infrared, water-soluble, functional and dendrimeric photosensitizer (PS) based on quinoxalinoporphyrazine structure. The photophysical properties and in vitro photodynamic therapy results suggest that this quinoxalinoporphyrazine-based dendrimer may serve as an efficient near infrared (NIR) PS platform.
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