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A Versatile Dynamic Mussel-Inspired Biointerface: From Specific Cell Behavior Modulation to Selective Cell Isolation
文献类型:期刊
作者:Liu, Lei[1]  Tian, Xiaohua[2]  Ma, Yue[3]  Duan, Yuqing[4]  Zhao, Xin[5]  Pan, Guoqing[6]  
机构:[1]Jiangsu Univ, Inst Adv Mat, Sch Mat Sci & Engn, Zhenjiang 212013, Jiangsu, Peoples R China.;
[2]Jiangsu Univ, Inst Adv Mat, Sch Mat Sci & Engn, Zhenjiang 212013, Jiangsu, Peoples R China.;
[3]Jiangsu Univ, Sch Chem & Chem Engn, Zhenjiang 212013, Jiangsu, Peoples R China.;
[4]Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang, Peoples R China.;
[5]Hong Kong Polytech Univ, Dept Biomed Engn, Hong Kong, Hong Kong, Peoples R China.;
[6]Jiangsu Univ, Inst Adv Mat, Sch Mat Sci & Engn, Zhenjiang 212013, Jiangsu, Peoples R China.;
通讯作者:Pan, Guoqing;
年:2018
期刊名称:ANGEWANDTE CHEMIE-INTERNATIONAL EDITION影响因子和分区
卷:57
期:26
页码范围:7878-7882
增刊:正刊
学科:化学;材料科学;多学科
收录情况:SCI(E)(WOS:000435766800054)  PubMed(29733501)  
所属部门:材料科学与工程学院(新材料研究院 绿色材料与冶金研究院);食品与生物工程学院(农产品加工工程研究院);化学化工学院(绿色化学与化工技术研究院)
重要成果类型:重要期刊
语言:外文
ISSN:1433-7851
被引频次:2
人气指数:643
浏览次数:643
基金:National Natural Science Foundation of China [21574091, 21573097, 51503087]; Natural Science Foundation of Jiangsu Province [BK20160056]
关键词:cell adhesion; dynamic biointerface; mussel-inspired peptides; reversible covalent bonds; tumor cell capture
摘要:
Reported here is a novel dynamic biointerface based on reversible catechol-boronate chemistry. Biomimetically designed peptides with a catechol-containing sequence and a cell-binding sequence at each end were initially obtained. The mussel-inspired peptides were then reversibly bound to a phenylboronic acid (PBA) containing polymer-grafted substrate through sugar-responsive catechol-boronate interactions. The resultant biointerface is thus capable of dynamic presentation of the bioactivity (i.e. ...More
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